产品货号：
Z15741
中文名称：
Cyclin A2/CCNA2抗体
英文名称：
Anti-Cyclin A2/CCNA2 Antibody
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-Cyclin A2/CCNA2 Antibody |
| 指标别名 | CCN1;CCNA;CCNA2;Cyclin A;cyclin A2;cyclinA2 |
| 克隆性 | Polyclonal |
| 检验物种 | human,mouse,rat |
| 应用范围 | WB,IHC,ICC/IF,FCM |
| 基因名称 | CCNA2 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | E.coli-derived human Cyclin A2 recombinant protein (Position:A10-K168).Human Cyclin A2 shares 74.5% amino acid (aa) sequence identity with mouse Cyclin A2. |
| 实际分子量 | 55KD |
| 成分 | 500μg/mL antibody with PBS，0.02% NaN3,1mg BSA and 50% glycerol. |
| 纯化方式 | Immunogen affinity purified. |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt，-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | Cyclin A2,known as CCNA2,is mapped to 4q27.The protein encoded by this gene belongs to the highly conserved cyclin family,whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle.Cyclins function as regulators of CDK kinases.Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event.In contrast to cyclin A1,which is present only in germ cells,this cyclin is expressed in all tissues tested.This cyclin binds and activates CDC2 or CDK2 kinases,and thus promotes both cell cycle G1/S and G2/M transitions.And Cyclin A2 is synthesized at the onset of S phase and localizes to the nucleus,where the cyclin A2-CDK2 complex is implicated in the initiation and progression of DNA synthesis.Phosphorylation of CDC6 and MCM4 by the cyclin A2-CDK2 complex prevents re-replication of DNA during the cell cycle. |
| Uniprot ID | P20248 |
| 推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot,and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (ZN1865) for IHC(P).*Blocking peptide可以联系我们购买。 |
| 基因名全称 | cyclin A2 |
| 蛋白名全称 | Cyclin-A2 |
| 推荐稀释比 | Western blot(WB) 1:500～2000 Immunohistochemistry in paraffin section (IHC) 1:50～400 Immunocytochemistry/Immunofluorescence(ICC/IF) 1:50～400 Flow cytometry (FCM) 1～3μg/1×106 cells (Boiling the paraffin sections in 10mM citrate buffer,pH6.0,or PH8.0 EDTA repair liquid for 20 mins is required for the staining of formalin/paraffin sections.) Optimal working dilutions must be determined by end user. |
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